Richard J Knox Selected Research

tretazicar

1/2010	Testing double mutants of the enzyme nitroreductase for enhanced cell sensitisation to prodrugs: effects of combining beneficial single mutations.
1/2009	Nitroreductase from Bacillus licheniformis: a stable enzyme for prodrug activation.
1/2003	Selective ablation of human cancer cells by telomerase-specific adenoviral suicide gene therapy vectors expressing bacterial nitroreductase.
1/2003	CB 1954: from the Walker tumor to NQO2 and VDEPT.

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Richard J Knox Research Topics

Disease

4	Neoplasms (Cancer) 01/2010 - 01/2003
1	Carcinoma (Carcinomatosis) 01/2010
1	Infections 01/2003
1	Hepatocellular Carcinoma (Hepatoma) 01/2003

Drug/Important Bio-Agent (IBA)

4	tretazicarIBA 01/2010 - 01/2003
4	ProdrugsIBA 01/2010 - 01/2003
3	EnzymesIBA 01/2010 - 01/2003
3	NitroreductasesIBA 01/2009 - 01/2003
1	Hydroxylamine (Hydroxylamine Hydrochloride)IBA 01/2009
1	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2003
1	Proteins (Proteins, Gene)FDA Link 01/2003
1	RNA (Ribonucleic Acid)IBA 01/2003
1	NRH - quinone oxidoreductase2IBA 01/2003
1	DNA (Deoxyribonucleic Acid)IBA 01/2003

Therapy/Procedure

4	Therapeutics 01/2010 - 01/2003